Cees Dekker
Kavli Institute of NanoScience, Delft University of Technology, Delft, The Netherlands
Cees Dekker (left) with Gianni Blatter
Date
14 May 2008
Title
Nanotechnology Tools for Biology, The Power of Single Molecule Biophysics
Abstract
I will discuss the impact of nanoscience, in particular single-molecule techniques, on biology. Single-molecule tools such as scanning probes, tweezers, and nanostructures provide powerful new entries to study the structure, dynamics and function of biomolecules, molecular motors, DNA-enzyme interactions, and the like. I will illustrate this by discussing some examples of recent work in our group on a variety of systems such as solid-state nanopores for DNA translocation, DNA repair proteins, and motion on kinesin motor proteins in fabricated nanostructures.